“Astonishing” Effects of Grape Consumption and “Remarkable” Impacts on Health and Lifespans



Dr. John Pezzuto and his Western New England University team have published research that demonstrates the "astonishing" effects of grape consumption as well as its "amazing" effects on lifespans.

The journal Foods published one paper. It shown that adding grapes to a high-fat diet, which is generally consumed in western countries, in an amount equal to slightly under two cups per day, resulted in a decrease in fatty liver and an increase in lifespan. According to Pezzuto, these investigations give the proverb "you are what you eat" a completely new meaning. He claimed that the research with grapes demonstrated real alterations in genetic expression. He has produced approximately 600 scholarly articles. "That is genuinely amazing."

Grapes boosted levels of antioxidant genes and postponed natural death in conjunction with a high-fat diet. Pezzuto recognized that extrapolating a mouse's lifespan to a human being's is not an exact science. He said that his best guess is that the shift seen in the study would add an additional 4-5 years to a person's lifespan.

In the journal Antioxidants, Dr. Pezzuto and his group of researchers published yet another study. It stated that eating grapes improved behavior and cognition, which were negatively impacted by a high-fat diet and altered gene expression in the brain. In a third study, a group under the direction of Dr. Jeffrey Idle shown that grapes alter not only the expression of genes but also the metabolism.

"Remarkable" Impacts of Grape Consumption on Health and Lifespan for additional information on this study.

Foods, 5 July 2022, DOI: 10.3390/foods11131984. "Consumption of Grapes Modulates Gene Expression, Reduces Non-Alcoholic Fatty Liver Disease, and Extends Longevity in Female C57BL/6J Mice Provided with a High-Fat Western-Pattern Diet," by Asim Dave, Eun-Jung Park, Avinash Kumar, Falguni Parande, Diren Be
By Falguni Parande, Asim Dave, Eun-Jung Park, Christopher McAllister, and John M. Pezzuto, "Effect of Dietary Grapes on Female C57BL6/J Mice Consuming a High-Fat Diet: Behavioral and Genetic Changes," 18 February 2022, Antioxidants

The mouse's hepatic and urine metabolite profiles are changed when grapes are added to both a standard and a high-fat Western pattern diet, according to research. published in Food & Function on July 20, 2022, by Diren Beyolu, Eun-Jung Park, Adolfo Quiones-Lombra, Asim Dave, Falguni Parande, John M. Pezzuto, and Jeffrey R. Idle.

The studies' grapes and some funding were given by the California Table Grape Commission.

By CALIFORNIA TABLE GRAPE COMMISSION 

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