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Popular Medicines Including Ibuprofen and Naproxen Have Been Linked to Heart Failure in Diabetics

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Short-term use of non-steroidal anti-inflammatory medicines (NSAIDs) is associated with a first-time heart failure hospitalization in people with type 2 diabetes, according to a study presented at ESC Congress 2022. The most popular type of anti-inflammatory drug is NSAIDs. The most widely used NSAIDs are aspirin, ibuprofen (often referred to as Advil), and naproxen (known by the brand name Aleve and Naprosyn). Nevertheless, some medications can have negative effects while being widely used. According to the first author, Dr. Anders Holt of Copenhagen University Hospital in Denmark, one in six patients with type 2 diabetes used at least one NSAID prescription within a year of the study. "In general, we always advise patients to speak with their physician before beginning a new medicine, and given the findings from this study, we hope to assist physicians in reducing risk when prescribing NSAIDs. There aren't enough data on people with type 2 diabetes, however NSAID use has bee...

Laser light, a dye and a nonsurgical implant could help overcome obesity

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Weight-loss surgery can be a successful method of treating obesity when diets and exercise are insufficient. However, those who don't want surgery do have alternative choices, such as having a stomach implant or an appetite-suppressing balloon placed. Researchers now report in ACS Applied Materials & Interfaces that they have improved that process in lab animals by covering an implant with a laser-activated dye that kills cells generating ghrelin, the "hunger hormone," in a way that kills the cells. Following local anesthetic, implants can be placed in the stomach through the mouth. A brand-new implant was created in 2019 by Hwoon-Yong Jung, Jung-Hoon Park, and other collaborators. The "intragastric satiety-inducing device" (ISD) comprises of a disk that lies in the stomach's entrance and a stent that is implanted in the lower esophagus. A hole in the center of the disk allows food to pass through. Tests on pigs revealed that the ISD increased feelings o...