Brain activity during sleep differs in young people with genetic risk of psychiatric disorders
Sleep-related brain activity patterns can be utilized as a biomarker to identify the start of neuropsychiatric illnesses in patients with 22q11.2 Deletion Syndrome (22q11.2DS), a genetic abnormality that sheds information on the neurobiology underlying the condition. 1 in 3000 births result in 22q11.2DS, which is brought on by a gene loss of about 30 genes on chromosome 22. It raises the chance of epileptic seizures, autism spectrum disorder (ASD), intellectual disability, and attention-deficit hyperactivity disorder (ADHD). Additionally, it ranks highly among the biological risk factors for schizophrenia. Uncertainty surrounds the molecular processes that underlie the psychological symptoms of 22q11.2DS, though. According to co-senior author Marianne van den Bree, Professor of Psychological Medicine at Cardiff University, UK, "We have recently shown that the majority of young people with 22q11.2DS have sleep problems, particularly insomnia and sleep fragmentation, that are linked...