This molecule could be behind liver fibrosis
The liver is a crucial organ in the body's processing of all the many substances we put into it, including food, drink, alcohol, and narcotics. When the liver malfunctions, the results might be fatal. Scarring, also known as liver fibrosis, is the primary cause of many liver illnesses, including hepatitis and Non-Alcoholic SteatoHepatitis, or NASH. At this time, there are no medications available to cure this scarring. In order to find possible targets for medications in the future, researchers are looking into the underlying causes of liver fibrosis. A chemical responsible for the bile duct cells' unchecked proliferation inside the liver has been identified by a U-M study. The bile duct cells are injured in diseased livers, according to Liangyou Rui, Ph.D., the Louis G. D'Alecy Collegiate Professor of Physiology. The liver must constantly produce new bile duct cells, but occasionally these cells malfunction, resulting in inflammation and scarring. Rui notes that this incre...