A Puzzling Mystery: Why Do Salamanders Lose Their Lungs?

Salamanders without lungs produce lungs as embryos despite having lost their lungs as adults over millions of years. The lungs of many vertebrates, including humans, are crucial. However, four extant amphibian clades now mostly breathe through their wet skin rather than their lungs. The developmental causes of lung loss in these clades are poorly understood. When the Plethodontidae, a dominant family of salamanders that are all lungless as adults, were examined, researchers from Harvard University's Museum of Comparative Zoology and Department of Organismic and Evolutionary Biology found that they do develop lungs as embryos. This finding sheds light on the evolution of lung loss over millions of years. The journal Science Advances just published their findings. With about two-thirds of the diversity in the current salamander population, Plethodontidae is the salamander family with the greatest number of species. The skin and mucous membranes of the mouth and throat serve as the pr...