Scientific Link Between Stress and Difficulty Becoming Pregnant



A woman's fecundity, or her likelihood of becoming pregnant during a menstrual cycle, may be impacted by stress, according to recent research. Acta Obstetricia et Gynecologica Scandinavica will publish the study today, September 21.

In obstetrics and gynecology, fecundability refers to the likelihood of getting pregnant during a single menstrual cycle, and fecundity refers to the likelihood of giving birth to a live child within a single cycle.

The study, which evaluated the participants' allostatic loads, included 444 women who were trying to get pregnant. The "wear and tear" caused by recurring stress and traumatic life events is referred to as allostatic load. Based on nine indications including blood pressure, cortisol, blood sugar, noradrenaline, and cholesterol, women with higher allostatic load scores had a lower likelihood of getting pregnant within a year. For instance, compared to women with allostatic load scores of 0, those with values of 5-6 would have 59% less fecundity.

"What we learned offers a fresh paradigm for preconception counseling. But obviously, how to accurately assess the stress is a challenging scientific question, and how to intervene and lessen the effects of chronic stress is a pressing issue, all of which need more research, according to the study's senior author, PhD candidate Bei Wang of Southeast University in Jiangsu, China.

The study, "Female fecundability is associated with pre-pregnancy allostatic load: Analysis of a Chinese cohort," was published in Acta Obstetricia et Gynecologica Scandinavica on September 21, 2022.                                                                        
By WILEY SEPTEMBER 21, 2022

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